A 31 years old female came to our OPD from Nanital with primary amenorrhea and primary infertility. We had advised the hormonal profile and the ultrasound pelvis. Her hormonal profile showed low serum FSH, LH and Estradiol. Ultrasound showed bilateral small sized ovaries with hypoplastic uterus. She was diagnosed as a case of hypogonadotropic hypogonadism. The husband’s semen analysis was normal.
In view of the above diagnosis, we recommended donor egg surrogacy and trial with self-eggs also to the couple. As her FSH and LH levels were low, we stimulated her ovaries as well along with ovaries of the donor. Her and donor’s eggs were extracted which were fertilized in the IVF laboratory. Seven good embryos (grade A) of patient herself were formed out of which 3 embryos were transferred in the surrogate and 4 embryos were frozen in one vial. Three Day 2 Embryos were transferred in the surrogate. After 14 days of luteal support, beta HCG was done which came positive.
A 29 years old female came to our OPD from Shimla with primary infertility. Her hormonal profile showed very low serum FSH, LH and Estradiol. Ultrasound showed absent ovaries with no uterus. Her karyotype showed 46 XY which means she was genetically male. But phenotypically she was looking as a beautiful female. The couple had love marriage. She was diagnosed as a probable case of Swyer syndrome, or XY gonadal dysgenesis. The husband’s semen analysis was normal.
In view of the above diagnosis, we recommended donor egg surrogacy to the couple. We stimulated the ovaries of the donor and extracted the eggs from her. The fertilization of the eggs was done with the husband’s sperms in the IVF laboratory. Three resulting good embryos (grade A) were transferred in the uterus of the surrogate and 6 grade A embryos were frozen in 2 vials. After 14 days, beta HCG was positive which confirmed the pregnancy.